Building Block Engineering toward Realizing High-Performance Electrochromic Materials and Glucose Biosensing Platform

The molecular engineering of conjugated systems has proven to be an effective method for understanding structure–property relationships toward the advancement optoelectronic properties and biosensing characteristics. Herein, a series three thieno[3,4-c]pyrrole-4,6-dione (TPD)-based monomers, modified with electron-rich selenophene, 3,4-ethylenedioxythiophene (EDOT), or both building blocks (Se-TPD, EDOT-TPD, EDOT-Se-TPD), were synthesized using Stille cross-coupling electrochemically polymerized, their electrochromic applications in glucose platform explored. influence structural modification on electrochemical, electronic, optical, was systematically investigated. results showed that cyclic voltammograms EDOT-containing materials displayed high charge capacity over wide range scan rates representing quick propagation, making them appropriate high-performance supercapacitor devices. UV-Vis studies revealed EDOT-based presented wide-range absorptions, thus low optical band gaps. These two EDOT-modified also exhibited superior contrasts fast switching times, further multi-color neutral fully oxidized states, enabling promising constructing advanced In context applications, selenophene-containing polymer markedly lower performance, specifically signal intensity stability, which attributed improper localization biomolecules surface. Overall, we demonstrated relatively small changes structure had significant impact TPD-based donor–acceptor polymers.